In Vivo Imaging System

There are two main types of optical In Vivo imaging systems: luminescence and fluorescence.
Firefly luciferase and luciferin are mainly used in Luminescence experiments to label cells and obtain images. The light generated by infected luciferase gene is too weak to see with the naked eye. When this is applied to cells and living animals, greater light loss occurs. To capture images of light with such low brightness, imaging system needs to employ an ultra-high sensitivity image sensor.
In the case of fluorescence, either a fluorescent gene or a fluorescent reagent can be used. Both produce light strong enough to be seen with the naked eye. Due to the nature of fluorescence, there is excitation light and emission light, and images can be obtained and analyzed using the emission light from the fluorescent material. At this time, the excitation light is filtered out using a optical filter, and only the emission light required for imaging is passed through. FOBI can effectively obtain excellent In Vivo images by using filters optimized for In Vivo images. 
Because luminescent In Vivo imaging devices and fluorescent In Vivo imaging devices have similar yet different principles, key elements such as image sensors and optical filters required for each require different specifications. Therefore, when luminescence and fluorescence are combined into a single device, the product becomes complex and large.
Neo Science manufactures light emitting devices and fluorescent devices separately and faithfully fulfills the functions of each product. And this independent devices simplifies the structure of the product and makes it compact and easy to use and maintain.